30 products were found matching "K11462"!

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes...

EED226 is a potent and allosteric inhibitor of the histone H3K27me3 methyltransferase activity of polycomb repressive complex 2 (PRC2, IC50 = 23.4 nM in an enzyme assay with H3K27me0 peptide as the substrate). It exhibits dose-dependent displacement of H3K27me3 binding to the EED subunit of PCR2 but has no effect on...

A-395 is an inhibitor of the interaction between embryonic ectoderm development (EED) and histone H3 lysine 27 (H3K27) that binds to the EED subunit of polycomb repressor complex 2 (PRC2) and inhibits H3K27 methylation (Ki = 0.4 nM). It inhibits H3K27 di- and trimethylation in RD rhabdoid tumor cells (IC50s = 390...

Human Embryonic Ectoderm Development (hEED), also known as WAIT-1, GenBank Accession No. NM_003797, a.a. 2-end with N-terminal FLAG-tag, MW= 51 kDa, expressed in Sf9 cells via a baculovirus expression system.

The human-Embryonic ectoderm development (EED) protein is a WD40 repeat-containing protein that forms part of the Polycomb repressive complex 2 (PRC2). The PRC2 core complex contains the catalytic subunit EZH2 (Enhancer of zeste 2), SUZ12 (Suppressor of zeste) and EED. The EED subunit does not contain...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Polycomb protein EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting...

WB 1:500 - 1:2000. Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2...

WB 1:500 - 1:2000. Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2...