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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG44818.50 | 50 µg | - | - |
6 - 14 business days* |
575.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which... more
Product information "Anti-EED"
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED- EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. {ECO:0000269, PubMed:10581039, ECO:0000269, PubMed:14532106, ECO:0000269, PubMed:15225548, ECO:0000269, PubMed:15231737, ECO:0000269, PubMed:15385962, ECO:0000269, PubMed:16357870, ECO:0000269, PubMed:18285464, ECO:0000269, PubMed:20974918, ECO:0000269, PubMed:28229514, ECO:0000269, PubMed:9584199}. [The UniProt Consortium]
| Keywords: | Anti-hEED, Anti-hEED, Anti-WAIT-1, Anti-WAIT-1, Anti-Polycomb protein EED {ECO:0000305}, Anti-Polycomb protein EED {ECO:0000305}, Anti-WD protein associating with integrin cytoplasmic tails 1, Anti-WD protein associating with integrin cytoplasmic tails 1, |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG44818 |
Properties
| Application: | IP, WB |
| Antibody Type: | Monoclonal |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human, mouse |
| Format: | Purified |
Database Information
| KEGG ID : | K11462 | Matching products |
| UniProt ID : | O75530 | Matching products |
| Gene ID : | GeneID 8726 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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