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Anti-EED

Absea
Preview: Anti-EED Preview: Anti-EED
Anti-EED
Anti-EED
   
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-KC-1066.50 50 µl - -

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206.00€
ABS-KC-1066.100 100 µl - -

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295.00€
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Description Product Citations Certificate of Analysis Reviews 0
Description
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which... more
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Product information "Anti-EED"
Protein function: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED- EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. [The UniProt Consortium]
Keywords: Anti-Polycomb protein EED, Anti-hEED, Anti-Embryonic ectoderm development protein, Anti-WD protein associating with integrin cytoplasmic tails 1, Anti-WAIT-1, EED Antibody
Supplier: Absea
Supplier-Nr: KC-1066

Properties

Application: IHC
Antibody Type: Monoclonal
Clone: 4B5
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant human EED
Format: Solution

Database Information

KEGG ID : K11462 | Matching products
UniProt ID : O75530 | Matching products
Gene ID : GeneID 8726 | Matching products

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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