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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG58377.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Proposed to have a global role in regulating mRNA expression including... more
Product information "Anti-DHX36"
Protein function: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification. [The UniProt Consortium]
Keywords: | Anti-G4R1, Anti-DHX36, Anti-DDX36, EC=3.6.4.13, EC=3.6.4.12, Anti-G4-resolvase 1, Anti-MLE-like protein 1, Anti-DEAH box protein 36, Anti-ATP-dependent RNA helicase DHX36, Anti-RNA helicase associated with AU-rich element ARE |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG58377 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat |
Immunogen: | Recombinant funsion protein corresponding to aa. 1-260 of Human DHX36 (NP_065916.2) |
MW: | 114 kD |
Format: | Affinity Purified |
Database Information
KEGG ID : | K14442 | Matching products |
UniProt ID : | Q9H2U1 | Matching products |
Gene ID | GeneID 170506 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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