Anti-DAP5

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-60796.60 60 µl -

7 - 16 business days*

198.00€
E-AB-60796.120 120 µl -

7 - 16 business days*

317.00€
E-AB-60796.200 200 µl -

7 - 16 business days*

525.00€
 
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic... more
Product information "Anti-DAP5"
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. Protein function: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. [The UniProt Consortium]
Keywords: Anti-p97, Anti-DAP-5, Anti-eIF4G 2, Anti-eIF-4G 2, Anti-eIF-4-gamma 2, Anti-Death-associated protein 5, Anti-Eukaryotic translation initiation factor 4 gamma 2, DAP5 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-60796

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: A synthetic peptide of human EIF4G2

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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