74 products were found matching "K03260"!

SBI-0640756 is an inhibitor of eukaryotic translation initiation factor 4 gamma 1 (eIF4G1). It inhibits the association of eIF4G1 with the eIF4F complex in UACC-903 melanoma cell lysates in an m7GTP-agarose pull-down assay when used at a concentration of 0.75 µM. SBI-0640756 also inhibits eIF4G1-dependent and...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Eukaryotic translation initiation factor 4 gamma 1 is a protein that in humans is encoded by the EIF4G1 gene. It is mapped to 3q27.1. The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Eukaryotic translation initiation factor 4 gamma 2, also called DAP-5 (Death-associated protein 5) and p97, is a protein that in humans is encoded by the EIF4G2 gene. Translation initiation is mediated by specific recognition of the cap structure by eukaryotic...

In eukaryotes, a set of initiation factors (eIFs) interact with ribosomal subunits to initiate mRNA translation. A major step in initiation is the assembly of a large multiprotein complex that includes the cap-binding protein eIF4E and the multidomain adaptor protein eIF4G. 4EGI-1 is an inhibitor of the initiation...

Protein function: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. [The UniProt Consortium]

Protein function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. [The UniProt Consortium]

Protein function: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. [The UniProt Consortium]

Protein function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. [The UniProt Consortium]

Protein function: Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. [The UniProt Consortium]

Protein function: Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. [The UniProt Consortium]

Protein function: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. [The UniProt Consortium]

Protein function: Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases. [The UniProt Consortium]