Anti-D-Dimer, clone DD1

Anti-D-Dimer, clone DD1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG10354.250 250 µg - -

6 - 14 business days*

624.00€
 
Protein function: Cleaved by the protease thrombin to yield monomers which, together with... more
Product information "Anti-D-Dimer, clone DD1"
Protein function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3- dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways. [The UniProt Consortium]
Keywords: Anti-FGA
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG10354

Properties

Application: ELISA, IA, WB
Antibody Type: Monoclonal
Clone: DD1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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