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Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FGa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FGa. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FGa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FGa. Next,...

Colormetric. Detection Range: 6.25-400 ng/mL. Protein function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood...

Anti-FIBRINOGEN is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  Assay by immunoelectrophoresis resulted in a single precipitin arc...

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the peptidylarginine deiminases enzymes (PAD2 and PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid...

Protein function: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early...

Fibrinogen is a hexameric glycoprotein that has roles in coagulation and hemostasis. It is comprised of two sets of Aalpha, Bbeta, and gamma polypeptide chains encoded by FGA, FGB, and FGG, respectively, in humans. Fibrinogen is synthesized in hepatocytes and secreted into the plasma. Following thrombin-mediated...

Fibrinogen is a hexameric glycoprotein that has roles in coagulation and hemostasis. It is comprised of two sets of Aalpha, Bbeta, and gamma polypeptide chains encoded by FGA, FGB, and FGG, respectively, in humans. Fibrinogen is synthesized in hepatocytes and secreted into the plasma. Following thrombin-mediated...

Protein function: Fibrinogen has a double function: yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation. [The UniProt Consortium]