Anti-Cytokeratin 6, clone KRT6/1702

Anti-Cytokeratin 6, clone KRT6/1702
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3301SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. This mAb recognizes a protein of 56kDa,... more
Product information "Anti-Cytokeratin 6, clone KRT6/1702"
1 mg/ml in 1X PBS, BSA free, sodium azide free. This mAb recognizes a protein of 56kDa, identified as Cytokeratin 6 (CK6). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns, and Cytokeratin 6A is the dominant form in epithelial tissue. The gene encoding human Cytokeratin 6A maps to chromosome 12q13, and mutations in this gene are linked to several inheritable hair and skin pathologies. Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. Protein function: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. [The UniProt Consortium]
Keywords: Anti-K6A, Anti-CK-6D, Anti-CK-6A, Anti-KRT6A, Anti-Hom s 5, Anti-Keratin-6A, Anti-Cytokeratin-6A, Anti-Cytokeratin-6D, Anti-Type-II keratin Kb6, Anti-Keratin, type II cytoskeletal 6A, Cytokeratin 6 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3301SAF-100UG

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: KRT6/1702
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Recombinant human CK6 protein was used as the immunogen for the Cytokeratin 6 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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