Anti-CysLT2 Receptor (C-Term)

Anti-CysLT2 Receptor (C-Term)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay120550-1 1 each -

3 - 10 business days*

324.00€
 
The cysteinyl leukotrienes (cysLTs, LTC4, LTD4, and LTE4) contract airway and pulmonary vascular... more
Product information "Anti-CysLT2 Receptor (C-Term)"
The cysteinyl leukotrienes (cysLTs, LTC4, LTD4, and LTE4) contract airway and pulmonary vascular smooth muscle, increase vascular permeability, and stimulate mucus secretion, thereby playing a major role in asthma. LTC4, LTD4, and LTE4 mediate their actions via at least two receptors designated CysLT1 and CysLT2. Cloning of the human CysLT2 receptor reveals it is a 346 amino acid protein with 38% homology to the CysLT1 receptor. The rank order of binding for leukotrienes to the cloned receptor, as determined using a radioligand binding assay, is LTC4 = LTD4 >> LTE4. The mRNA for the human CysLT2 receptor is expressed in lung macrophages, airway smooth muscle, cardiac Purkinje cells, adrenal medulla cells, peripheral blood leukocytes, spleen, placenta, and brain.
Keywords: Anti-HPN321, Anti-CYSLT2, Anti-CYSLTR2, Anti-CysLTR2, Anti-hGPCR21, Anti-PSEC0146, Anti-G-protein coupled receptor HG57, Anti-Cysteinyl leukotriene receptor 2, Anti-G-protein coupled receptor GPCR21
Supplier: Cayman Chemical
Supplier-Nr: 120550-1

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Immunogen: human CysLT2 receptor C-terminal amino acids 33-346 (TKCVFPVSVWLRKETRV)
Format: Solid

Database Information

KEGG ID : K04323 | Find alternatives
UniProt ID : Q9NS75 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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