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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-RC-6837.50 | 50 µl | - | - |
Request delivery time estimate |
206.00€
|
||
| ABS-RC-6837.100 | 100 µl | - | - |
Request delivery time estimate |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: A cytochrome P450 monooxygenase that catalyzes the biosynthesis of adrenal... more
Product information "Anti-CYP11B2 Recombinant"
Protein function: A cytochrome P450 monooxygenase that catalyzes the biosynthesis of adrenal mineralocorticoid aldosterone (PubMed:11856349, PubMed:23322723, PubMed:1594605, PubMed:9814506). Catalyzes three sequential oxidative reactions of 11-deoxycorticosterone/21- hydroxyprogesterone, namely 11-beta hydroxylation followed with two successive oxidations at C18 to yield 18-hydroxy and then 18-aldehyde derivatives, resulting in the formation of aldosterone (PubMed:11856349, PubMed:23322723, PubMed:1594605, PubMed:9814506). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:11856349, PubMed:23322723, PubMed:1594605, PubMed:9814506). [The UniProt Consortium]
| Keywords: | Anti-Cytochrome P450 11B2, Anti-mitochondrial, Anti-Aldosterone synthase, Anti-ALDOS, Anti-Aldosterone-synthesizing enzyme, Anti-CYPXIB2, Anti-Corticosterone 18-monooxygenase, Anti-CYP11B2, Anti-Cytochrome P-450Aldo, Anti-Cytochrome P-450C18, Anti-Steroid |
| Supplier: | Absea |
| Supplier-Nr: | RC-6837 |
Properties
| Application: | WB |
| Antibody Type: | Monoclonal |
| Clone: | 3J89 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Format: | Solution |
Database Information
| KEGG ID : | K07433 | Matching products |
| UniProt ID : | P19099 | Matching products |
| Gene ID : | GeneID 1585 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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