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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F47386-0.08ML | 80 µl | - | - |
3 - 10 business days* |
326.00€
|
||
NSJ-F47386-0.4ML | 400 µl | - | - |
3 - 10 business days* |
702.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a CXC chemokine receptor specific... more
Product information "Anti-CXCR4"
In 1X PBS, pH 7.4, with 0.09% sodium azide. This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]. Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. [The UniProt Consortium]
Keywords: | Anti-LCR1, Anti-FB22, Anti-HM89, Anti-LESTR, Anti-CD184, Anti-CXCR4, Anti-NPYRL, Anti-LAP-3, Anti-Fusin, Anti-CXC-R4, Anti-CXCR-4, Anti-SDF-1 receptor, Anti-LPS-associated protein 3, Anti-C-X-C chemokine receptor type 4, Anti-CXCR4 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F47386 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K04189 | Matching products |
UniProt ID : | P61073 | Matching products |
Gene ID | GeneID 7852 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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