Anti-CXCR4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-G92	100 µg		-	-	6 - 10 business days*		848.00€

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Anti-CXCR4 Antibody was affinity purified. A BLAST analysis was used to suggest cross-reactivity... more

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Product information "Anti-CXCR4"

Anti-CXCR4 Antibody was affinity purified. A BLAST analysis was used to suggest cross-reactivity with CXCR4 with Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with CXCR4 from other sources has not been determined. Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. [The UniProt Consortium]

Keywords:	Anti-FB22, Anti-LCR1, Anti-HM89, Anti-LESTR, Anti-NPYRL, Anti-Fusin, Anti-CXCR4, Anti-CD184, Anti-LAP-3, Anti-CXC-R4, Anti-CXCR-4, Anti-SDF-1 receptor, Anti-LPS-associated protein 3, Anti-C-X-C chemokine receptor type 4
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-G92

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	peptide corresponding to an internal sequence in the second extracellular loop (EL) of human CXCR4.
Format:	Purified