Anti-CSK

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R33934-100UG 100 µg - -

3 - 10 business days*

549.00€
 
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more
Product information "Anti-CSK"
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: C-src tyrosine kinase Protein function: Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T- cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK. [The UniProt Consortium]
Keywords: Anti-CSK, Anti-C-Src kinase, Anti-Protein-tyrosine kinase CYL, Anti-Tyrosine-protein kinase CSK, CSK Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R33934

Properties

Application: WB, IHC, ELISA (peptide)
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human, Mouse, Rat
Immunogen: Amino acids EQLEHIKTHELHL were used as the immunogen for this CSK antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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