Anti-CRTH2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-AP1	100 µg		-	-	6 - 10 business days*		684.00€

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Anti-CRTH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more

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Product information "Anti-CRTH2"

Anti-CRTH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CRTH2 from other sources has not been determined. Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses. [The UniProt Consortium]

Keywords:	Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44, Anti-Chemoattractant receptor-homologous molecule expressed on Th2 cells
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-AP1

Properties

Application:	ELISA, IHC, IFM, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	15 amino acid synthetic peptide from near the internal region of human CRTH2.
Format:	Purified