- Search results for K06715
Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
30 products were found matching "K06715"!
Close filters
Filter by:
No results were found for the filter!
Item number: Cay12027-25
OC000459 is a potent, selective DP2 antagonist that displaces [3H]prostaglandin D2 ([3H]PGD2) from human recombinant DP2 receptors (Ki = 13 nM), rat recombinant DP2 receptors (Ki = 3 nM), and human native DP2 (Ki = 4 nM, Th2 cell membranes) without interfering with the ligand binding properties of other prostanoid...
Keywords: | 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid |
Application: | DP2 antagonist |
CAS | 851723-84-7 |
MW: | 348.4 D |
From 92.00€
*
Item number: Cay10012553-1
The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. In humans, CRTH2/DP2 is expressed on Th2 cells, eosinophils, and basophils where it mediates the chemotactic activity of PGD2. CAY10595, as a racemic mixture, is...
Keywords: | 5-chloro-1'-[5-chloro-2-fluorophenyl)methyl]-2,2',5'-trioxo-spiro[3H-indole-3,3'pyrrolidine]-1(2H)-acetic acid |
Application: | CRTH2receptor antagonist, DP2 receptor antagonist |
CAS | 916047-16-0 |
MW: | 451.2 D |
From 89.00€
*
Item number: Cay10004030-5
S-5751 is an antagonist of the prostaglandin D2 (PGD2) receptor DP1 (Ki = 1.6 nM) that shows at least 20-fold selectivity over receptors for thromboxane and prostacyclin, as well as the PGE2 receptor EP2. Orally administered S-5751 blocks PGD2-induced plasma exudation in the conjunctiva (ED50 = 0.099 mg/kg) and...
Keywords: | (5Z)-7-[(1R,2R,3S,5S)-2-[[(5-hydroxybenzo[b]thien-3-yl)carbonyl]amino]-6,6-dimethylbicyclo[3.1.1]hept-3-yl]-5-heptenoic acid |
Application: | Prostaglandin D2 receptor (PTGDR) antagonist |
CAS | 209268-36-0 |
MW: | 441.6 D |
From 66.00€
*
Item number: Cay28291-5
Setipiprant is an orally bioavailable antagonist of the prostaglandin D2 (PGD2, Cay-12010) receptor CRTH2/DP2 (IC50 = 6 nM for the human receptor). It is selective for CRTH2/DP2 over DP1 in a radioligand binding assay (IC50 = 1,290 nM) and the prostaglandin E2 (PGE2, Cay-14010) receptor subtypes EP2 and EP4 in a...
Keywords: | ACT-129968, 8-fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-acetic acid |
Application: | CRTH2/CD294 antagonist |
CAS | 866460-33-5 |
MW: | 402.4 D |
From 66.00€
*
Item number: 600-401-AP0
Anti-CRTH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CRTH2 from other sources has not been determined. Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | ELISA, IHC, IFM, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
684.00€
*
Item number: 600-401-AP1
Anti-CRTH2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with CRTH2 from other sources has not been determined. Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | ELISA, IHC, IFM, WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
684.00€
*
Item number: Cay20238-1
LAS191859 is a potent antagonist of CRTH2/DP2 with IC50 values of 9.58, 14, 15.5, and 7.6 nM for recombinant human, rat, mouse, and guinea pig CRTH2/DP2 receptors, respectively. It is selective for CRTH2/DP2 over a panel of 65 enzymes, ion channels, and transporters with 50s = 2 and 8.2 nM in isolated eosinophils...
Keywords: | 1-[2-[[(cyclopropylcarbonyl)ethylamino]methyl]-4-(trifluoromethyl)phenyl]-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-acetic acid |
Application: | Prostaglandin D2 receptor 2 antagonist |
CAS | 1420071-13-1 |
MW: | 459.5 D |
From 212.00€
*
-15 %
Discount Promotion
Item number: ABE-10-10014-100
Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | FC, WB |
Host: | Mouse |
Species reactivity: | mouse, human |
418.00€
*
355.30€
*
Item number: ABE-10-10015-25
Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | FC |
Host: | Mouse |
Species reactivity: | human |
149.00€
*
Item number: ABE-10-10014-25
Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | FC, WB |
Host: | Mouse |
Species reactivity: | mouse, human |
149.00€
*
-15 %
Discount Promotion
Item number: ABE-10-10015-100
Protein function: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2...
Keywords: | Anti-CD294, Anti-CRTH2, Anti-PTGDR2, Anti-Prostaglandin D2 receptor 2, Anti-G-protein coupled receptor 44,... |
Application: | FC |
Host: | Mouse |
Species reactivity: | human |
418.00€
*
355.30€
*
Item number: Cay27638-1
BI-671800 is an antagonist of the prostaglandin D2 (PGD2, Cay-12010) receptor CRTH2/DP2 (IC50 = 42 nM in a radioligand binding assay). It binds selectively to CRTH2/DP2 over DP1, thromboxane, and prostacyclin receptors (IC50s = 25.6, 62.6, and >100 µM, respectively). BI-671800 inhibits PGD2-induced shape change in...
Keywords: | AP-761, 4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]-5-pyrimidineacetic acid |
Application: | Prostaglandin D2 receptor CRTH2/GPR44/CD294 antagonist |
CAS | 1093108-50-9 |
MW: | 501.5 D |
From 287.00€
*