Anti-Connexin 32 / GJB1, clone M12.13

Anti-Connexin 32 / GJB1, clone M12.13
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3306SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. This Ab recognizes a protein of 27-32kDa,... more
Product information "Anti-Connexin 32 / GJB1, clone M12.13"
1 mg/ml in 1X PBS, BSA free, sodium azide free. This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. Protein function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. [The UniProt Consortium]
Keywords: Anti-GJB1, Anti-Cx32, Anti-CX32, Anti-Connexin-32, Anti-Gap junction beta-1 protein, Anti-GAP junction 28 kDa liver protein, Connexin 32 Antibody / GJB1
Supplier: NSJ Bioreagents
Supplier-Nr: V3306SAF

Properties

Application: FC, IF, WB, IF
Antibody Type: Monoclonal
Clone: M12.13
Conjugate: No
Host: Mouse
Species reactivity: rat, mouse, human
Immunogen: Rat junctional complexes were used as the immunogen for the Connexin 32 antibody. The epitope is known to be located in the cytoplasmic loop (Ref 1).
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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