Anti-CLCN2

Anti-CLCN2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45963.100 100 µl - -

6 - 14 business days*

740.00€
 
Protein function: Voltage-gated chloride channel. Chloride channels have several functions... more
Product information "Anti-CLCN2"
Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at hyperpolarized membrane potentials in the glomerulosa causes cell membrane depolarization, activation of voltage- gated Ca2+ channels and increased expression of aldosterone synthase, the rate-limiting enzyme for aldosterone biosynthesis (PubMed:29403011, PubMed:29403012). {ECO:0000269, PubMed:19153159, ECO:0000269, PubMed:19191339, ECO:0000269, PubMed:29403011, ECO:0000269, PubMed:29403012}. [The UniProt Consortium]
Keywords: Anti-CLCN2, Anti-ClC-2, Anti-ClC-2, Anti-Chloride channel protein 2, Anti-Chloride channel protein 2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45963

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Synthesize peptide from human CLCN2, corresponding to amino acid residues L835-P885
MW: 99 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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