26 products were found matching "K05011"!

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Lubiprostone
Lubiprostone

Item number: TGM-T6307-100mg

Description: Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation. Target: Chloride channel. Smiles: CCCCC(F)(F)C(=O)CC[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O. References: Bijvelds MJ, et al. Gastroenterology, 2009, 137(3), 976-1985.
Keywords: RU-0211, SPI-0211
Application: ClC-2 activator
CAS 136790-76-6
MW: 390.46 D
From 46.00€ *
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Anti-CLCN2, Internal
Anti-CLCN2, Internal

Item number: ARG65190.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. [The UniProt Consortium]
Keywords: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Application: ELISA, WB
Host: Goat
Species reactivity: human
822.00€ *
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Anti-CLCN2
Anti-CLCN2

Item number: NSJ-R35412-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Chloride channel 2 Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal...
Keywords: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2, CLCN2 Antibody
Application: WB, ELISA (peptide)
Host: Goat
Species reactivity: human
790.00€ *
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Lubiprostone
Lubiprostone

Item number: Cay10010487-10

Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
Keywords: RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid
Application: ClC-2 activator
CAS 136790-76-6
MW: 390.5 D
From 85.00€ *
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Anti-CLCN2
Anti-CLCN2

Item number: ATA-HPA014545.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Keywords: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Application: ICC, IHC
Host: Rabbit
Species reactivity: human
From 358.00€ *
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Anti-CLCN2
Anti-CLCN2

Item number: ATA-HPA024108.100

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Keywords: Anti-CLCN2, Anti-ClC-2, Anti-Chloride channel protein 2
Application: IHC
Host: Rabbit
Species reactivity: human
From 358.00€ *
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NEW
Anti-clh-3
Anti-clh-3

Item number: CSB-PA190466XA01CXY.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Keywords: Anti-Chloride channel protein clh-3, clh-3 Antibody
Application: ELISA, WB
Host: Rabbit
Species reactivity: Caenorhabditis elegans
From 1,529.00€ *
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NEW
Anti-Clcn2
Anti-Clcn2

Item number: CSB-PA005481XA01RA.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Keywords: Anti-Clcn2, Anti-ClC-2, Anti-Chloride channel protein 2, Clcn2 Antibody
Application: ELISA, WB
Host: Rabbit
Species reactivity: Rattus norvegicus (Rat)
From 1,529.00€ *
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NEW
Anti-ClC-a
Anti-ClC-a

Item number: CSB-PA894220XA01DLU.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Keywords: Anti-ClC-2, Anti-ClC-a, Anti-DmClC-2, Anti-CG31116, Anti-Chloride channel-a, Anti-Chloride channel protein 2, ClC-a Antibody
Application: ELISA, WB
Host: Rabbit
Species reactivity: Drosophila melanogaster (Fruit fly)
From 1,529.00€ *
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NEW
Nanodisc Human CLCN2 Protein
Nanodisc Human CLCN2 Protein

Item number: G-HDFP527.10

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Keywords: ClC-2, CLCN2, Chloride channel protein 2
Expressed in: Human cells
Origin: human
1,486.00€ *
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NEW
Nanodisc Human CLCN2-Strep Protein
Nanodisc Human CLCN2-Strep Protein

Item number: G-HDFP1242.10

Protein function: Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. Involved in the regulation of aldosterone production. The opening of CLCN2 channels at...
Keywords: ClC-2, CLCN2, Chloride channel protein 2
Expressed in: Human cells
Origin: human
1,336.00€ *
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Human CLCN2 full length protein-synthetic nanodisc
Human CLCN2 full length protein-synthetic nanodisc

Item number: DIM-FLP100619.10

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by...
Keywords: CLCN2, ClC-2, Chloride channel protein 2
Application: Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization
Expressed in: Human cells
Origin: human
MW: 98.5 kD
From 1,291.00€ *
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