Anti-CILP, Internal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64007.100	100 µg		-	-	6 - 14 business days*		871.00€

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Protein function: Probably plays a role in cartilage scaffolding. May act by antagonizing... more

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Product information "Anti-CILP, Internal"

Protein function: Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage. [The UniProt Consortium]

Keywords:	Anti-CILP
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64007

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	rat (Expected: human, mouse, canine)
Immunogen:	C-NYRRTDHEDPRVK
Format:	Ammonium Sulfate Precipitated