Anti-CEA / Carcinoembryonic Antigen, clone C66/4098

Anti-CEA / Carcinoembryonic Antigen, clone C66/4098
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V8631-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V8631-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The CD66... more
Product information "Anti-CEA / Carcinoembryonic Antigen, clone C66/4098"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. The CD66 (carcinoembryonic antigen, CEA, biliary glycoprotein I, BGP-1, CEACAM) immunoglobulin superfamily of genes encode cell adhesion proteins, which are expressed at higher levels in tumorous tissues than in normal tissues. The human CD66 gene family is a diverse set of glycoproteins of epithelial and hematopoietic lineage that comprises 29 genes, which map to chromosome position 19q13.2. CD66A, CD66B, CD66C, CD66D, CD66E and CD66F are the best characterized CD66 antigens, and CD66A-D expression upregulates on the surface of granulocytes upon stimulation. Certain CD66 family members mediate homotypic and heterotypic intercellular adhesion events. CD66E, also known as CEA, is a well known tumor marker and a heavily glycosylated GPI-linked cell surface molecule. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression, induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). [The UniProt Consortium]
Keywords: Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-Carcinoembryonic antigen-related cell adhesion molecule 5, CEA Antibody / Carcinoembryonic Antigen
Supplier: NSJ Bioreagents
Supplier-Nr: V8631

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: C66/4098
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Recombinant full-length human CEA protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CEA / Carcinoembryonic Antigen, clone C66/4098"
Write a review
or to review a product.
Viewed