Anti-CEA / Carcinoembryonic Antigen, clone C66/3707R

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V8370-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V8370-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Carcinoembryonic antigen... more
Product information "Anti-CEA / Carcinoembryonic Antigen, clone C66/3707R"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Carcinoembryonic antigen (CEA) is a glycoprotein produced in colorectal cancer tissues. In normal adult tissue, CEA is expressed in the apical border and, to a lesser extent in the cytoplasm, of the columnar cells of colon, small intestine, stomach (surface epithelium, mucous neck cells and weakly in pyloric mucous cells), pancreatic ducts, secretory epithelia of sweat glands, squamous epithelial cells of the tongue, esophagus,uterine cervix, and urothelium. The CEA antibody is a useful aid for classification of adenocarcinomas, notably in the gastrointestinal tract, including colonic and pancreatic carcinomas. IHC results also aid in the classification of secretory meningiomas and medullary carcinoma of the thyroid. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression, induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). [The UniProt Consortium]
Keywords: Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-Carcinoembryonic antigen-related cell adhesion molecule 5, CEA Antibody / Carcinoembryonic Antigen
Supplier: NSJ Bioreagents
Supplier-Nr: V8370

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: C66/3707R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant full-length human CEA protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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