Anti-CD98, clone IPO-T10

Anti-CD98, clone IPO-T10
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2859SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD98 exits as a heterodimer containing a... more
Product information "Anti-CD98, clone IPO-T10"
1 mg/ml in sterile PBS, BSA free, sodium azide free. CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. Protein function: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier. [The UniProt Consortium]
Keywords: Anti-CD98, Anti-MDU1, Anti-4F2hc, Anti-SLC3A2, Anti-4F2 heavy chain antigen, Anti-Solute carrier family 3 member 2, Anti-4F2 cell-surface antigen heavy chain, Anti-Lymphocyte activation antigen 4F2 large subunit, CD98 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2859SAF-100UG

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: IPO-T10
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Human leukocytes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CD98, clone IPO-T10"
Write a review
or to review a product.
Viewed