Anti-CD98

Anti-CD98
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-331A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A304-331A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A304-331A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Required for the function of light chain amino-acid transporters. Involved in... more
Product information "Anti-CD98"
Protein function: Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier. [The UniProt Consortium]
Keywords: Anti-MDU1, Anti-CD98, Anti-4F2hc, Anti-SLC3A2, Anti-4F2 heavy chain antigen, Anti-Solute carrier family 3 member 2, Anti-4F2 cell-surface antigen heavy chain, Anti-Lymphocyte activation antigen 4F2 large subunit
Supplier: Bethyl Laboratories
Supplier-Nr: A304-331A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A304-331A-T maps to a region between residue 580 to 630 of human CD98 Heavy Chain using the numbering given in entry NP_002385.3 (GeneID 6520).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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