Anti-CD43, clone 84-3C1

Anti-CD43, clone 84-3C1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2872SAF-100UG 100 µg - -

3 - 10 business days

541.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. It recognizes a cell surface glycoprotein of... more
Product information "Anti-CD43, clone 84-3C1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop III). 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma. Protein function: One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response. [The UniProt Consortium]
Keywords: Anti-SPN, Anti-CD43, Anti-GALGP, Anti-Sialophorin, Anti-Leukosialin, Anti-Galactoglycoprotein, Anti-Leukocyte sialoglycoprotein, CD43 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2872SAF-100UG

Properties

Application: WB, FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: 84-3C1
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Stimulated human leukocytes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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