Anti-CD274 [B7-H1] (human), clone ANC6H1

Anti-CD274 [B7-H1] (human), clone ANC6H1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ANC-274-020 100 µg -

3 - 9 business days

CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a... more
Product information "Anti-CD274 [B7-H1] (human), clone ANC6H1"
CD274 (B7-H1, PD-L1, Programmed Death Ligand) is a member of the B7 family and is expressed on a variety of tissues including lymphoid cells. It plays an important role in regulation of T cell activation and is involved in progression of cancer, arthritis and HIV infection. CD274 binding to its receptor CD279 (PD-1) on activated T cells can decrease proliferation. Conversely, ligation of CD279 on primed T cells can stimulate IL-10 production. High levels of CD274 present in renal cell carcinoma is associated with poor prognosis. Tumor expressed CD274 can increase apoptosis of tumor specific T cells resulting in better tumor cell survival.
Keywords: Anti-PDL1, Anti-B7H1, Anti-B7-H1, Anti-CD274, Anti-PD-L1, Anti-PDCD1L1, Anti-PDCD1LG1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Supplier: Ancell
Supplier-Nr: ANC-274-020


Application: FC, ELISA
Antibody Type: Monoclonal
Clone: ANC6H1
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant  human CD274(B7-H1)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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