Anti-CD274 / PD-L1, clone RM320

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG57681.50 50 µl - -

6 - 14 business days*

608.00€
 
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self.... more
Product information "Anti-CD274 / PD-L1, clone RM320"
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077). [The UniProt Consortium]
Keywords: Anti-B7H1, Anti-PD-L1, Anti-B7-H1, Anti-CD274, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death ligand 1, Anti-Programmed cell death 1 ligand 1
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG57681

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Monoclonal
Clone: RM320
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide around the C-terminus of Human PD-L1
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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