Anti-CD273 [B7-DC/PD-L2] (human), clone ANC8D12, FITC conjugated

Anti-CD273 [B7-DC/PD-L2] (human), clone ANC8D12, FITC conjugated
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ANC-273-040 120 tests -

3 - 9 business days*

310.00€
 
Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived... more
Product information "Anti-CD273 [B7-DC/PD-L2] (human), clone ANC8D12, FITC conjugated"
Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived Dendritic cells (moDC), and blocks binding of recombinant CD279 to CD273 in EIA and FACS. CD273 (B7-DC, PD-L2, Programmed Death Ligand 2) is a 25 kd member of the B7 family and is expressed mainly on a sub set of Dendritic cells. When engaged it has a stimulatory effect on the expressing DC, and delivers a down regulatory signal to cells expressing its counter receptor, CD279(PD-1). The interaction of CD273(B7-DC) and CD274(B7-H1) with their receptor, CD279(PD-1) is an important component of immune regulation.
Keywords: Anti-B7DC, Anti-B7-DC, Anti-CD273, Anti-PD-L2, Anti-PDCD1LG2, Anti-PD-1 ligand 2, Anti-PDCD1 ligand 2, Anti-Butyrophilin B7-DC, Anti-Programmed death ligand 2, Anti-Programmed cell death 1 ligand 2
Supplier: Ancell
Supplier-Nr: 273-040

Properties

Application: FC, FA (blocking)
Antibody Type: Monoclonal
Clone: ANC8D12
Conjugate: FITC
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human CD273(B7-DC)
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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