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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ANC-273-040 | 120 tests | - |
3 - 9 business days* |
415.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived... more
Product information "Anti-CD273 [B7-DC/PD-L2] (human), clone ANC8D12, FITC conjugated"
Antibody ANC8D12 binds to recombinant CD273 and cell surface CD273 expressed on monocyte derived Dendritic cells (moDC), and blocks binding of recombinant CD279 to CD273 in EIA and FACS. CD273 (B7-DC, PD-L2, Programmed Death Ligand 2) is a 25 kd member of the B7 family and is expressed mainly on a sub set of Dendritic cells. When engaged it has a stimulatory effect on the expressing DC, and delivers a down regulatory signal to cells expressing its counter receptor, CD279(PD-1). The interaction of CD273(B7-DC) and CD274(B7-H1) with their receptor, CD279(PD-1) is an important component of immune regulation.
Keywords: | Anti-B7DC, Anti-B7-DC, Anti-CD273, Anti-PD-L2, Anti-PDCD1LG2, Anti-PD-1 ligand 2, Anti-PDCD1 ligand 2, Anti-Butyrophilin B7-DC, Anti-Programmed death ligand 2, Anti-Programmed cell death 1 ligand 2 |
Supplier: | Ancell |
Supplier-Nr: | 273-040 |
Properties
Application: | FC, FA (blocking) |
Antibody Type: | Monoclonal |
Clone: | ANC8D12 |
Conjugate: | FITC |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant human CD273(B7-DC) |
Format: | Purified |
Database Information
KEGG ID : | K06708 | Matching products |
UniProt ID : | Q9BQ51 | Matching products |
Gene ID | GeneID 80380 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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