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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V7138IHC-7ML | 7 ml | - | - |
3 - 10 business days* |
752.00€
|
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*.... more
Product information "Anti-CD146, clone CDLA146"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. CD146/MUC18/MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. [UniProt] Protein function: Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration. [The UniProt Consortium]
Keywords: | Anti-MCAM, Anti-CD146, Anti-MUC18, Anti-Cell surface glycoprotein P1H12, Anti-Cell surface glycoprotein MUC18, Anti-Melanoma-associated antigen A32, Anti-Melanoma cell adhesion molecule, Anti-Melanoma-associated antigen MUC18, CD146 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V7138IHC |
Properties
Application: | IHC |
Antibody Type: | Monoclonal |
Clone: | CDLA146 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Recombinant human protein was used as the immunogen for the CD146 antibody. |
Format: | Purified |
Database Information
KEGG ID : | K06534 | Matching products |
UniProt ID : | P43121 | Matching products |
Gene ID | GeneID 4162 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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