Anti-CBX7

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA056480.25	25 µl		-		7 - 10 business days*		358.00€
ATA-HPA056480.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex... more

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Product information "Anti-CBX7"

Protein function: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 28%

Keywords:	Anti-CBX7, Anti-Chromobox protein homolog 7
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA056480

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KPKRLLLQRL YSMDLRSSHK AKGKEKLCFS LTCPLGSGSP EGVVKAGAPE LVDKG (ATA-APrEST87759)