Anti-Cathepsin D / CTSD, clone CTSD/2781

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7476-20UG 20 µg - -

3 - 10 business days*

332.00€
NSJ-V7476-100UG 100 µg - -

3 - 10 business days*

752.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Cathepsin D is a... more
Product information "Anti-Cathepsin D / CTSD, clone CTSD/2781"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. Protein function: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. [The UniProt Consortium]
Keywords: Anti-CPSD, Anti-CTSD, EC=3.4.23.5, Cathepsin D Antibody / CTSD
Supplier: NSJ Bioreagents
Supplier-Nr: V7476

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: CTSD/2781
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: A portion of amino acids 104-250 from the human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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