148 products were found matching "K01379"!

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a...

Protein function: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. [The UniProt Consortium]

Protein function: Acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed:27333034). Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. [The UniProt...

Cathepsin D (CatD) is an important intracellular aspartic acid protease and is widely present in the biological world. Cathepsin D has multiple biological functions and is involved in intracellular protein degradation, apoptosis and autophagy, etc. The detection principle of this kit: CatD hydrolyzes the substrate...

Pepstatin A is a bacteria-derived pentapeptide inhibitor of aspartic proteases. It inhibits pepsin, cathepsin D, and HIV protease (IC50s = 50s = 0.32 and 15 µM for the porcine and human enzymes, respectively). It inhibits HIV replication in infected H9 cells when used at a concentration of 100 µM and inhibits...

Protein function: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. [The UniProt Consortium]

Protein function: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. [The UniProt Consortium]

Natural and recombinant human Cathepsin D. There is no detectable cross-reactivity with other relevant proteins. Protein function: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. [The UniProt Consortium]

Natural and recombinant mouse Cathepsin D. There is no detectable cross-reactivity with other relevant proteins. Protein function: Acid protease active in intracellular protein breakdown. [The UniProt Consortium]

0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from...