Anti-Cathepsin D

Anti-Cathepsin D
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2097-24C.100 100 µl - -

3 - 19 business days*

514.00€
 
Cathepsin D is a ubituitiously expressed lysosomal aspartyl protease involved in the normal... more
Product information "Anti-Cathepsin D"
Cathepsin D is a ubituitiously expressed lysosomal aspartyl protease involved in the normal degradation of proteins (1). It is synthesized as an inactive 43kD preprocathepsin D that is cleaved and glycosylated to form a 46kD procathepsin D and then further cleaved to produce 28kD and 15kD subunits (heavy and light chains, respectively) (2). Cathepsin D may also be secreted into the cytosol during apoptosis and contribute to cleavage of substrates implicated in the apoptotic pathway (3). Numerous studies have suggested that cathepsin D plays a role in neuronal degradation and malignant transformation, particularily in breast cancer (4-9). Applications: Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, Immunohistochemistry (Paraffin): 1:200, Flow Cytometry: 1:200, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-CTSD, Anti-CPSD, EC=3.4.23.5
Supplier: United States Biological
Supplier-Nr: C2097-24C

Properties

Application: FC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey
Immunogen: Synthetic peptide (KLH-coupled) corresponding to residues with the heavy chain subunit of human Cathepsin D.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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