Anti-CARD11

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-11031.20 20 µl -

7 - 16 business days*

71.00€
E-AB-11031.60 60 µl -

7 - 16 business days*

143.00€
E-AB-11031.120 120 µl -

7 - 16 business days*

238.00€
E-AB-11031.200 200 µl -

7 - 16 business days*

396.00€
 
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK)... more
Product information "Anti-CARD11"
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Protein function: Involved in the costimulatory signal essential for T- cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway. [The UniProt Consortium]
Keywords: Anti-CARD11, Anti-Carma 1, Anti-CARD-containing MAGUK protein 1, Anti-Caspase recruitment domain-containing protein 11, CARD11 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-11031

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant protein of human CARD11
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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