Anti-Carbonyl Reductase 1/CBR1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-773A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A304-773A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: NADPH-dependent reductase with broad substrate specificity. Catalyzes the... more

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Product information "Anti-Carbonyl Reductase 1/CBR1"

Protein function: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. [The UniProt Consortium]

Keywords:	Anti-CBR, Anti-CBR1, EC=1.1.1.189, EC=1.1.1.197, EC=1.1.1.184, Anti-Carbonyl reductase [NADPH] 1, Anti-Prostaglandin 9-ketoreductase, Anti-Prostaglandin-E(2) 9-reductase, Anti-NADPH-dependent carbonyl reductase 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-773A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A304-773A-T maps to a region between residue 227 to 277 of human Carbonyl reductase [NADPH] 1 using the numbering given in entry P16152 (GeneID 873).
Format:	Antigen Affinity Purified