Anti-BMX

Anti-BMX
Item number Size Datasheet Manual SDS Delivery time Quantity Price
029999.100 100 µl - -

3 - 19 business days*

477.00€
 
BMX (bone marrow X kinase) is a cytoplasmic tyrosine kinase identified by reverse transcription... more
Product information "Anti-BMX"
BMX (bone marrow X kinase) is a cytoplasmic tyrosine kinase identified by reverse transcription of mRNA isolated from human bone marrow and mapped to the chromosomal band Xp22.2. The full length protein is 675 amino acids with a tyrosine kinase domain, an amino terminal pleckstrin domain, as well as an SH3 and SH2 domain. Direct comparison of BMX's primary sequence with other kinases showed that this is highly related to the family of BTK/ITK/TEC. BMX kinase is expressed in fetal and adult tissues, with the highest expression in heart, testis, small intestine and colon. It is undetectable in spleen, brain, kidney, and pancreas. Further analysis of mRNA expression showed that BMX is expressed in hematopoietic tissues and neutrophilic granulocytes, and in patients with acute and myeloid leukemia. The levels of BMX mRNA were substantially lower in patients with acute and chronic lymphoid leukemias, thus suggesting that BMX may be important during myelopoiesis.CST:It is expressed in a variety of hematopoietic, epithelial and endothelial cells. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-ETK, Anti-BMX, Anti-NTK38, EC=2.7.10.2, Anti-Cytoplasmic tyrosine-protein kinase BMX, Anti-Epithelial and endothelial tyrosine kinase, Anti-Bone marrow tyrosine kinase gene in chromosome X protein
Supplier: United States Biological
Supplier-Nr: 029999

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B77
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human BMX expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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