Anti-BMP2, clone 15B3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG57127.50	50 µl		-	-	6 - 14 business days*		518.00€

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Protein function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the... more

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Product information "Anti-BMP2, clone 15B3"

Protein function: Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). [The UniProt Consortium]

Keywords:	Anti-BMP2, Anti-BMP-2, Anti-BMP2A, Anti-BMP-2A, Anti-Bone morphogenetic protein 2, Anti-Bone morphogenetic protein 2A
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG57127

Properties

Application:	WB
Antibody Type:	Monoclonal
Clone:	15B3
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant fragment around aa. 283-396 of Human BMP2
Format:	Purified