Anti-BLT1 Receptor Antiserum

Anti-BLT1 Receptor Antiserum
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay100019-1 1 each -

3 - 10 business days*

324.00€
 
The leukotriene B4 receptor 1 (BLT1 receptor), cloned from HL-60 human leukemia cells, has 352... more
Product information "Anti-BLT1 Receptor Antiserum"
The leukotriene B4 receptor 1 (BLT1 receptor), cloned from HL-60 human leukemia cells, has 352 amino acids and seven putative membrane-spanning domains. The primary structure of the receptor is identical to that of a putative purinoceptor, P2Y7, which binds to micromolar concentrations of ATP. Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus. Sheep lung membranes have also been identified as a rich source for receptor isolation and purification. A second LTB4 receptor, BLT2, has recently been cloned and characterized. Cayman Chemical's BLT1 receptor polyclonal antiserum is made against a peptide from the C-terminus of the BLT1 receptor, which is located on the intracellular side of the plasma membrane. Therefore, when performing studies on whole cells, permeabilization of the cells is required for the antibody to enter the cytosol. The antiserum is recommended for immunohistochemical analysis of BLT1 receptor expression in tissues of human and bovine origin. Successful recognition of the overexpression of BLT1 in pancreatic ductal cells of human chronic pancreatitis and pancreatic cancer patients has been documented using this antiserum. Synonyms: BLTR1, Leukotriene B4 Receptor 1, LTB4 Receptor 1. Immunogen: Synthetic peptide from the C-terminal region of human BLT1. Formulation: Polyclonal antiserum. Storage Buffer: Polyclonal antiserum when reconstituted in 100 µl of deionized water. Host: Rabbit. Applications: CF, FC, IHC (formalin-fixed paraffin-embedded tissue), and WB. UniProt Accession #: Q15722. Origin: Animal/Rabbit.
Keywords: Anti-BLT, Anti-P2Y7, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-LTB4-R 1, Anti-P2Y purinoceptor 7, Anti-P2Y purinoceptor 7, Anti-Leukotriene B4 receptor 1, Anti-Leukotriene B4 receptor 1, Anti-G-protein coupled receptor 16, Ant
Supplier: Cayman Chemical
Supplier-Nr: 100019

Properties

Application: CF, FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Immunogen: Synthetic peptide from the C-terminal region of human BLT1
Format: Lyophilized

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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