Anti-Bcl-XL

Anti-Bcl-XL
Item number Size Datasheet Manual SDS Delivery time Quantity Price
B0807-19D.100 100 µg - -

3 - 19 business days*

644.00€
 
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of... more
Product information "Anti-Bcl-XL"
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis (reviewed in 2 and 3). These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene (4). Its high expression in tumors is correlated with advanced disease and poor prognosis (5). Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents (6,7). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western blot: 1 to 2ug/ml. , Oprimal dillution to be determined by researcher, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-5% ?glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-BCL2L, Anti-BCL2L1, Anti-Bcl2-L-1, Anti-Bcl-2-like protein 1, Anti-Apoptosis regulator Bcl-X
Supplier: United States Biological
Supplier-Nr: B0807-19D

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Format: Highly Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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