Anti-Bcl-X, clone 2H12

Anti-Bcl-X, clone 2H12
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3121-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3121-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 27kDa,... more
Product information "Anti-Bcl-X, clone 2H12"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 27kDa, identified as the Bcl-X protein. This mAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This mAb reacts with both Bcl-XS and Bcl-XL proteins. Protein function: Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. [The UniProt Consortium]
Keywords: Anti-BCL2L, Anti-BCL2L1, Anti-Bcl2-L-1, Anti-Bcl-2-like protein 1, Anti-Apoptosis regulator Bcl-X, Bcl-X Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3121-20UG

Properties

Application: FC, IF, WB, IHC
Antibody Type: Monoclonal
Clone: 2H12
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse, Rat, Swine
Immunogen: Amino acids 3-14 (QSNRELVVDFLS) from the human protein were used as the immunogen for this Bcl-X antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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