Anti-Bcl X (Bcl-X, BclX, Apoptosis Regulator Bcl X, Apoptosis Regulator Bcl-X, B cell Lymphoma 2-lik

Anti-Bcl X (Bcl-X, BclX, Apoptosis Regulator Bcl X, Apoptosis Regulator Bcl-X, B cell Lymphoma 2-lik
Item number Size Datasheet Manual SDS Delivery time Quantity Price
B0807-14D.50 50 µl - -

3 - 19 business days*

498.00€
 
Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is... more
Product information "Anti-Bcl X (Bcl-X, BclX, Apoptosis Regulator Bcl X, Apoptosis Regulator Bcl-X, B cell Lymphoma 2-lik"
Bcl-x, a member of the Bcl-2 protein family, inhibits cell death, or apoptosis (1). Bcl-x is expressed as two isomeric forms, Bcl-xL and Bcl-xS, and is typically present in the cytosol in association with the mitochondrial membrane. Bcl-xL forms heterodimers with various proteins, including Bax, Bak and Bcl-2 (2). It has been found that heterodimerization with Bax does not seem to be required for anti-apoptotic activity (3). Since Bcl-xL can form an ion channel in synthetic lipid membranes, there is a strong possibility that this property plays a role in heterodimerization-independent cell survival (4). The Bcl-X(S) isoform promotes apoptosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot 1:10000, a band is seen ~26 kD, Optimal dilution determined by the researcher. Positive Controls: A431 Whole Cell Lysate, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-Bcl2-L-1, Anti-Bcl-2-like protein 1, Anti-Apoptosis regulator Bcl-X
Supplier: United States Biological
Supplier-Nr: B0807-14D

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide made to an internal portion of the human protein (within residues 1-50). Mitochondrion membrane, Single-pass membrane protein (By similarity). Nucleus membrane, Single-pass membrane protein, Cytoplasmic side (By similarity).
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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