Anti-BAG3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA018493.25	25 µl		-		7 - 10 business days*		330.00€
ATA-HPA018493.100	100 µl		-		7 - 10 business days*		463.00€

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Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a... more

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Product information "Anti-BAG3"

Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti- apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 77% and to rat: 80%

Keywords:	Anti-BIS, Anti-BAG3, Anti-BAG-3, Anti-Docking protein CAIR-1, Anti-Bcl-2-binding protein Bis, Anti-Bcl-2-associated athanogene 3, Anti-BAG family molecular chaperone regulator 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA018493

Properties

Application:	IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: DSVDPEGRAD VRQARRDGVR KVQTILEKLE QKAIDVPGQV QVYELQPSNL EADQPLQAIM EMGAVAADKG KKNAGNAEDP HTETQQPEAT AAATSNPSSM TDTPGNPAAP (ATA-APrEST74209)