48 products were found matching "K09557"!

JG-98 is an inhibitor of the protein-protein interaction between heat shock protein 70 (Hsp70) and Bcl-2-associated athanogene 3 (BAG-3, IC50 = 1.6 µM). It reduces the proliferation of MDA-MB-231 and MCF-7 breast cancer cells (EC50s = 0.4 and 0.7 µM, respectively) and 22 other cancer cell lines (EC50s = 0.3-4 µM)....

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human BAG3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human BAG3. Next,...

Protein function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [The UniProt Consortium]

Protein function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [The UniProt Consortium]

Protein function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [The UniProt Consortium]

0.5mg/ml if reconstituted with 0.2ml sterile DI water. BAG family molecular chaperone regulator 3 is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. Polymorphisms are also...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. BAG3 inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [UniProt] Protein function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [The UniProt...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: BCL2-associated athanogene 3 Protein function: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: BCL2-associated athanogene 3 Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and...

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of BAG3 in serum, plasma and other biological fluids. Detection Range: 0.16--10ng/mL. Sensitivity: 0.1ng/mL. Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the...

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal...