Anti-BAG3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG41481.100	100 µl		-	-	6 - 14 business days*		707.00€

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Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a... more

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Product information "Anti-BAG3"

Protein function: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti-apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920). [The UniProt Consortium]

Keywords:	Anti-BIS, Anti-BAG3, Anti-BAG-3, Anti-Docking protein CAIR-1, Anti-Bcl-2-binding protein Bis, Anti-Bcl-2-associated athanogene 3, Anti-BAG family molecular chaperone regulator 3
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG41481

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant fusion protein corresponding to aa. 380-575 of Human BAG3 (NP_004272.2)
MW:	61 kD
Format:	Affinity Purified