Anti-B2AR / Beta-2-Adrenergic receptor / ADRB2

In 1X PBS, pH 7.4, with 0.09% sodium azide. The Beta-2-Adrenergic receptor is a protein that is found on the surface of cells, particularly in the lungs, heart, and smooth muscle tissue. It is a member of the G-protein coupled receptor family which transmits signals from outside the cell to the inside, triggering a cascade of cellular responses. The Beta-2-Adrenergic receptor plays a critical role in regulating various physiological functions, including bronchodilation, heart rate, and glucose metabolism. Dysregulation of the Beta-2-Adrenergic receptor has been implicated in a variety of diseases, such as asthma, chronic obstructive pulmonary disease, and heart failure. Protein function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30- fold greater affinity than it does norepinephrine. [The UniProt Consortium]