146 products were found matching "K04142"!

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Clenbuterol-d9
Clenbuterol-d9

Item number: Cay40816-1

Clenbuterol-d9 is intended for use as an internal standard for the quantification of clenbuterol (Cay-14985) by GC- or LC-MS. Clenbuterol is an agonist of beta2-adrenergic receptors (beta2-ARs). It induces relaxation of equine tracheal muscle strips (EC50 = 2.1 nM). Clenbuterol (300 nM) increases the number of...
Keywords: NAB 365-d9, 4-amino-3,5-dichloro-alpha-[[[1,1-di(methyl-d3)ethyl-2,2,2-d3]amino]methyl]-benzenemethanol
Application: GC-MS, LC-MS internal standard, quantification, beta2-adrenergic receptor agonist
CAS 129138-58-5
MW: 286.2 D
From 267.00€ *
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Vilanterol (triphenylacetate)
Vilanterol (triphenylacetate)

Item number: Cay39536-10

Vilanterol is a long-acting agonist of the beta2-adrenergic receptor (beta2-AR). It selectively induces cAMP accumulation in CHO cells expressing the beta2-AR over the beta1- and beta3-ARs (EC50s = 0.4, 398, and 794 nM for the human receptors, respectively). Vilanterol inhibits contractions induced by electrical...
Keywords: GW 642444M, alpha1R-[[[6-[2-[(2,6-dichlorophenyl)methoxy]ethoxy]hexyl]amino]methyl]-4-hydroxy-1,3-benzenedimethanol,...
Application: Beta2-AR agonist
CAS 503070-58-4
MW: 774.8 D
From 66.00€ *
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ADRB2 Reporter Assay System (human)
ADRB2 Reporter Assay System (human)

Item number: IB-IB32101

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 2 (ADRB2). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB2. In addition to ADRB2 Reporter Cells, this kit provides...
Keywords: ADRB2, ADRB2R, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor
Application: Functional activity screening
Species reactivity: human
1,448.00€ *
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ADRB2 Reporter Assay System (human)
ADRB2 Reporter Assay System (human)

Item number: IB-IB32102

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Beta 2 (ADRB2). INDIGO's ADRB1 reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRB2. In addition to ADRB2 Reporter Cells, this kit provides...
Keywords: ADRB2, ADRB2R, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor
Application: Functional activity screening
Species reactivity: human
3,803.00€ *
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Mouse ADRb2 (Adrenergic Receptor Beta 2) ELISA Kit
Mouse ADRb2 (Adrenergic Receptor Beta 2) ELISA Kit

Item number: ELK-ELK6738.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ADRb2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ADRb2. Next,...
Keywords: Adrb2, Adrb2r, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, Beta-2 adrenergic receptor
Application: ELISA
Species reactivity: mouse
From 365.00€ *
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ICI 118551 (hydrochloride)
ICI 118551 (hydrochloride)

Item number: Cay15591-10

ICI 118551 is a potent, selective antagonist of the beta2-adrenergic receptor (Ki = 0.7 nM for the beta2 receptor, compared with 49.5 and 611 nM for beta1 and beta3 receptors, respectively). It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists.Formal Name:...
Keywords: (2R,3R)-rel-1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol, monohydrochloride
Application: beta2-adrenergic receptor antagonist
CAS 72795-01-8
MW: 313.9 D
From 195.00€ *
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(±)-Epinephrine (hydrochloride)
(±)-Epinephrine (hydrochloride)

Item number: Cay21245-1

(±)-Epinephrine is a natural neurotransmitter that is released from the adrenal medulla and activates adrenoceptors (Kis = 15, 735, and 3,970 nM for alpha1A-, beta2-, and beta1-adrenergic receptors, respectively). Through these receptors, (±)-epinephrine may induce either contraction or relaxation of vascular smooth...
Keywords: (±)-Adrenaline, DL-Adrenaline, DL-Epinephrine, 4-[1-hydroxy-2-(methylamino)ethyl]-1,2-benzenediol, monohydrochloride
Application: Natural neurotransmitter, Adrenoceptor activator
CAS 329-63-5
MW: 219.7 D
44.00€ *
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Olodaterol
Olodaterol

Item number: Cay21794-1

Olodaterol is a selective agonist of beta2-adrenergic receptors (beta2-ARs, EC50s = 97.7 and 2,725 nM for human beta2- and beta1-ARs, respectively). In vivo, olodaterol completely reverses acetylcholine-induced bronchoconstriction without cardiovascular side effects in guinea pigs. It also exhibits dose-dependent...
Keywords: BI-1744, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one
Application: beta2-Adrenergic receptor agonist
CAS 868049-49-4
MW: 386.4 D
From 113.00€ *
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Formoterol (hemifumarate hydrate)
Formoterol (hemifumarate hydrate)

Item number: Cay15584-10

Formoterol is a selective agonist of the beta2-adrenergic receptor (beta2-AR, Kis = 7.58 and 2,630 nM for beta2- and beta1-ARs, respectively). It is selective for beta-ARs in isolated guinea pig trachea over those in atrial tissue (pD2s = 9.29 and 6.98, respectively) and has a long duration of action. Aerosolized...
Keywords: rel-N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-formamide,...
Application: beta2-adrenergic receptor agonist
MW: 402.5 D
From 130.00€ *
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Indacaterol
Indacaterol

Item number: Cay20070-50

Indacaterol is a long-acting and selective beta2-adrenergic receptor (beta2-AR) agonist (EC50 = 8.71 nM for increasing intracellular cAMP levels in vitro). It is selective for beta2-ARs over beta1- and beta3-ARs (Kis = 43.6, 616.6, and 3,311.3 nM, respectively). Indacaterol inhibits bronchoconstriction induced by...
Keywords: QAB149, 5-[(1R )-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy 2(1H )-quinolinone
Application: beta2-Adrenergic receptor agonist
CAS 312753-06-3
MW: 392.5 D
From 66.00€ *
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Salmeterol (xinafoate)
Salmeterol (xinafoate)

Item number: Cay16009-10

Salmeterol is a long-acting beta2-adrenergic receptor agonist (beta2-AR, EC50s = 0.79, 63.1, and 9.4 nM for beta2-, beta1-, and beta3-ARs, respectively). It inhibits electrically-stimulated contraction of isolated guinea pig trachea strips (EC50 = 2.51 nM) and histamine-induced bronchoconstriction in guinea pigs via...
Keywords: GR-33343G, 4-hydroxy-alpha1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol,...
Application: beta2-adrenergic receptor agonist
CAS 94749-08-3
MW: 603.8 D
From 147.00€ *
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Sotalol (hydrochloride)
Sotalol (hydrochloride)

Item number: Cay16136-100

Sotalol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs, IC50s = 8.9 and 5.2 µM for beta1- and beta2-ARs, respectively) and a class III antiarrhythmic agent. It decreases delayed outward potassium currents (IK) in guinea pig ventricular cells and prolongs action potential duration in...
Keywords: (±)-Sotalol, DL-Sotalol, MJ1999, N-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-methanesulfonamide, monohydrochloride
Application: beta1/2-adrenergic receptor antagonist
CAS 959-24-0
MW: 308.8 D
From 43.00€ *
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