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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-Y75 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-ATG12 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-ATG12"
Anti-ATG12 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ATG12 from other sources has not been determined. Protein function: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus. [The UniProt Consortium]
Keywords: | Anti-ATG12, Anti-APG12, Anti-APG12-like, Anti-Autophagy-related protein 12, Anti-Ubiquitin-like protein ATG12 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-Y75 |
Properties
Application: | ELISA, IHC, IFM, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | 16 amino acid synthetic peptide from near the N-terminus of human ATG12. |
Format: | Purified |
Database Information
KEGG ID : | K08336 | Matching products |
UniProt ID : | O94817 | Matching products |
Gene ID | GeneID 9140 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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