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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A700-164-T | 10 µl (5+ tests) | - |
2 - 8 business days* |
172.00€
|
|||
A700-164 | 100 µl (50+ tests) | - |
2 - 8 business days* |
655.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Transcription factor that plays a key role in neuronal differentiation: acts as... more
Product information "Anti-ASCL1/MASH1 Recombinant Monoclonal"
Protein function: Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways. Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes. The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro. Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Involved in the regulation of neuroendocrine cell development in the glandular stomach. [The UniProt Consortium]
Keywords: | Anti-hASH1, Anti-ASH-1, Anti-bHLHa46, Anti-Achaete-scute homolog 1, Anti-Class A basic helix-loop-helix protein 46 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A700-164 |
Properties
Application: | WB, IP, IHC, ICC |
Antibody Type: | Monoclonal |
Clone: | BLR164J |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K09067 | Matching products |
UniProt ID : | P50553 | Matching products |
Gene ID | GeneID 429 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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