Anti-ARF6/ADP Ribosylation Factor 6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-238A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A305-238A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: GTP-binding protein involved in protein trafficking that regulates endocytic... more

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Product information "Anti-ARF6/ADP Ribosylation Factor 6"

Protein function: GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed:11266366, PubMed:21170023, PubMed:16737952, PubMed:7589240, PubMed:18400762). Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. May also modulate vesicle budding and uncoating within the Golgi apparatus. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (PubMed:14978216). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1. [The UniProt Consortium]

Keywords:	Anti-ADP-ribosylation factor 6
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-238A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, D. melanogaster, X. laevis, chicken, pig)
Immunogen:	synthetic peptide. The epitope recognized by A305-238A-T maps to a region between residue 125 to 175 of human ADP-ribosylation factor 6 using the numbering given in entry P62330.2 (GeneID 382).
Format:	Antigen Affinity Purified