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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-G76 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
Anti-APP Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-APP"
Anti-APP Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with APP with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with APP from other sources has not been determined. APP antibody detects the human amyloid A4 protein. Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease. Anti-APP is ideal for investigators that are involved in Neuroscience research.
Keywords: | Anti-APPI, Anti-ABPP, Anti-PreA4, Anti-PN-II, Anti-Amyloid beta A4 protein, Anti-Protease nexin-II, Anti-Alzheimer disease amyloid protein |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-G76 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | peptide corresponding to amino acids of human amyloid A4 protein precursor (APP) corresponding to the n-terminus of the 4K Ab peptide generated by b- and g-secretases. The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig, and chicken. |
Format: | Purified |
Database Information
KEGG ID : | K04520 | Matching products |
UniProt ID : | P05067 | Matching products |
Gene ID | GeneID 351 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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