Anti-APP

Anti-APP
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-G76 100 µg - -

6 - 10 business days*

684.00€
 
Anti-APP Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-APP"
Anti-APP Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with APP with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with APP from other sources has not been determined. APP antibody detects the human amyloid A4 protein. Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease. Anti-APP is ideal for investigators that are involved in Neuroscience research.
Keywords: Anti-APPI, Anti-ABPP, Anti-PreA4, Anti-PN-II, Anti-Amyloid beta A4 protein, Anti-Protease nexin-II, Anti-Alzheimer disease amyloid protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-G76

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: peptide corresponding to amino acids of human amyloid A4 protein precursor (APP) corresponding to the n-terminus of the 4K Ab peptide generated by b- and g-secretases. The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig, and chicken.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-APP"
Write a review
or to review a product.
Viewed